Bioactive glass (BG) was made by the solâ??gel method and doped with boron (B) to\nincrease its bioactivity. Microstructures of BG and B-doped BG were observed by scanning electron\nmicroscopy, and phase identification was performed using an X-ray diffraction diffractometer. The ion\nconcentrations released after soaking in simulated body fluid (SBF) for 1, 4, and 7 days were measured\nby inductively coupled plasma mass spectrometry, and the pH value of the SBF was measured\nafter soaking samples to determine the variation in the environment. Brunauerâ??Emmettâ??Teller\n(BET) analysis was performed to further verify the characteristics of mesoporous structures.\nHigh performance liquid chromatography was used to evaluate the drug delivery ability of teicoplanin.\nResults demonstrated that B-doped BG performed significantly better than BG in parameters assessed\nby the BET analysis. B-doped BG has nanopores and more rough structures, which is advantageous\nfor drug delivery as there are more porous structures available for drug adsorption. Moreover,\nB-doped BG was shown to be effective for keeping pH values stable and releasing B ions during\nsoaking in SBF. The cumulative release of teicoplanin from BG and B-doped BG reached 20.09% and\n3.17% on the first day, respectively. The drug release gradually slowed, reaching 29.43% and 4.83%\nafter 7 days, respectively. The results demonstrate that the proposed bioactive glass has potential\nas a drug delivery system.
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